cAMP/protein kinaseA effect on cell-cycle regulation: timecourse
Summary:
Analysis of wild type and Kin- S49 lymphoma cell line treated with 8-(4-chlorophenylthio)-cAMP (8-CPT-cAMP), a PKA-selective cAMP analog, for 2, 6, or 24 hours. Kin- S49 cells lack protein kinase A (PKA). Results identify the global impact of cAMP/PKA on transcriptional networks, particularly the ce
Zambon AC, Zhang L, Minovitsky S, Kanter JR et al. Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A. Proc Natl Acad Sci U S A 2005 Jun 14;102(24):8561-6. PMID: 15939874
