The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes.
Provides coverage of well-substantiated genes in the transcribed mouse genome on a single array.
Analyzes the expression level of approximately 14,000 well-characterized mouse genes.
Sequences used in the design of the array were selected from GenBank®, dbEST, and RefSeq. The sequence clusters were created from the UniGene database (Build 107, June 2002) and then refined by analysis and comparison with the publicly available draft assembly of the mouse genome from the Whitehead Institute for Genome Research (MGSC, April 2002).
The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321.
June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35
Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
The genus and species of the organism represented by the probe set.
Annotation Date
The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site.
Sequence Type
Sequence Source
The database from which the sequence used to design this probe set was taken.
Target Description
Representative Public ID
The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used.
Gene Title
Title of Gene represented by the probe set.
Gene Symbol
A gene symbol, when one is available (from UniGene).
ENTREZ_GENE_ID
Entrez Gene Database UID
RefSeq Transcript ID
References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet.
Gene Ontology Biological Process
Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Cellular Component
Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Molecular Function
Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0051683 // establishment of Golgi localization // not recorded /// 0072384 // organelle transport along microtubule // not recorded
0000139 // Golgi membrane // not recorded /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation
0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation
0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 1902600 // hydrogen ion transmembrane transport // inferred from direct assay
0005765 // lysosomal membrane // not recorded /// 0005769 // early endosome // inferred from direct assay /// 0005813 // centrosome // not recorded /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // not recorded /// 0016324 // apical plasma membrane // not recorded /// 0016471 // vacuolar proton-transporting V-type ATPase complex // not recorded /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0043005 // neuron projection // not recorded /// 0043234 // protein complex // not recorded /// 0043679 // axon terminus // not recorded /// 0070062 // extracellular vesicular exosome // not recorded
0005515 // protein binding // inferred from electronic annotation /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from direct assay /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0032403 // protein complex binding // not recorded
0006893 // Golgi to plasma membrane transport // not recorded /// 0018230 // peptidyl-L-cysteine S-palmitoylation // not recorded /// 0043001 // Golgi to plasma membrane protein transport // not recorded /// 0050821 // protein stabilization // not recorded
0000139 // Golgi membrane // not recorded /// 0002178 // palmitoyltransferase complex // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // not recorded /// 0070062 // extracellular vesicular exosome // not recorded
0006563 // L-serine metabolic process // not recorded /// 0006564 // L-serine biosynthetic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0016311 // dephosphorylation // not recorded /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation
0005737 // cytoplasm // not recorded /// 0043005 // neuron projection // not recorded
0000287 // magnesium ion binding // not recorded /// 0004647 // phosphoserine phosphatase activity // not recorded /// 0005509 // calcium ion binding // not recorded /// 0008253 // 5'-nucleotidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation
0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016358 // dendrite development // inferred from direct assay /// 0045212 // neurotransmitter receptor biosynthetic process // traceable author statement
0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030008 // TRAPP complex // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0045202 // synapse // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from electronic annotation
0005515 // protein binding // inferred from physical interaction
0006486 // protein glycosylation // inferred from electronic annotation /// 0006506 // GPI anchor biosynthetic process // not recorded /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0019348 // dolichol metabolic process // not recorded /// 0031647 // regulation of protein stability // not recorded /// 0050790 // regulation of catalytic activity // not recorded /// 0097502 // mannosylation // not recorded
0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // not recorded /// 0005783 // endoplasmic reticulum // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0033185 // dolichol-phosphate-mannose synthase complex // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded
0004582 // dolichyl-phosphate beta-D-mannosyltransferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030234 // enzyme regulator activity // not recorded
0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation
0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // not recorded
0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation
0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation
0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded
0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // not recorded /// 0006499 // N-terminal protein myristoylation // inferred from direct assay /// 0010991 // negative regulation of SMAD protein complex assembly // not recorded /// 0016055 // Wnt signaling pathway // not recorded /// 0016311 // dephosphorylation // not recorded /// 0030177 // positive regulation of Wnt signaling pathway // not recorded /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // not recorded /// 0035970 // peptidyl-threonine dephosphorylation // not recorded /// 0042347 // negative regulation of NF-kappaB import into nucleus // not recorded /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // not recorded /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // not recorded
0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005891 // voltage-gated calcium channel complex // not recorded /// 0016020 // membrane // inferred from direct assay /// 0043005 // neuron projection // not recorded
0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0033192 // calmodulin-dependent protein phosphatase activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // not recorded
0006509 // membrane protein ectodomain proteolysis // not recorded /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // inferred from mutant phenotype /// 0016485 // protein processing // not recorded /// 0043085 // positive regulation of catalytic activity // not recorded
0005783 // endoplasmic reticulum // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation
0005515 // protein binding // inferred from physical interaction
0006611 // protein export from nucleus // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation
0005622 // intracellular // traceable author statement /// 0005623 // cell // traceable author statement /// 0005634 // nucleus // not recorded /// 0005643 // nuclear pore // not recorded /// 0005737 // cytoplasm // not recorded
0005049 // nuclear export signal receptor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement
0001701 // in utero embryonic development // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from mutant phenotype /// 0018008 // N-terminal peptidyl-glycine N-myristoylation // not recorded
0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0015629 // actin cytoskeleton // not recorded /// 0030054 // cell junction // not recorded
0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from mutant phenotype /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // not recorded /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // not recorded
0006184 // GTP catabolic process // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007589 // body fluid secretion // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from mutant phenotype /// 0009790 // embryo development // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // not recorded /// 0032880 // regulation of protein localization // not recorded /// 0045176 // apical protein localization // not recorded
0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from mutant phenotype /// 0005622 // intracellular // not recorded /// 0005623 // cell // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // not recorded /// 0005770 // late endosome // not recorded /// 0005791 // rough endoplasmic reticulum // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // not recorded /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030133 // transport vesicle // not recorded /// 0030140 // trans-Golgi network transport vesicle // not recorded /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // not recorded /// 0043231 // intracellular membrane-bounded organelle // not recorded /// 0045335 // phagocytic vesicle // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded /// 0055037 // recycling endosome // not recorded /// 0070062 // extracellular vesicular exosome // not recorded /// 0097208 // alveolar lamellar body // not recorded
0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // not recorded /// 0019003 // GDP binding // not recorded
0016567 // protein ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // not recorded /// 0070936 // protein K48-linked ubiquitination // not recorded
0070062 // extracellular vesicular exosome // not recorded
0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // not recorded
0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007040 // lysosome organization // not recorded /// 0010507 // negative regulation of autophagy // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // not recorded /// 2000773 // negative regulation of cellular senescence // not recorded
0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded
0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // not recorded /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0043565 // sequence-specific DNA binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation
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