Cocaine addiction effect on reward-related brain regions
Summary:
Analysis of reward-related brain regions from Wistar males with restricted (1 h) or extended (6 h) daily access to cocaine. Escalated cocaine intake (ESC) developed in subjects with extended access. Results provide insight into molecular mechanisms underlying the transition to compulsive drug use.
GPL88:
[RN_U34] Affymetrix Rat Neurobiology U34 Array
Citation:
Ahmed SH, Lutjens R, van der Stap LD, Lekic D et al. Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction. Proc Natl Acad Sci U S A 2005 Aug 9;102(32):11533-8. PMID: 16076954
