Analysis of skin grafts lacking pRb, p107, or both genes. pRb and p107 belong to the retinoblastoma family important in cell cycle regulation. Results provide insight into the role of p107 in epidermal tumor development when pRb is absent.
Lara MF, Santos M, Ruiz S, Segrelles C et al. p107 acts as a tumor suppressor in pRb-deficient epidermis. Mol Carcinog 2008 Feb;47(2):105-13. PMID: 17932945