DataSet Record GDS3453: Expression Profiles Data Analysis Tools Sample Subsets
Title: Nematode models of primary mitochondrial dysfunction: complex I, II, and III mutants
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Summary: Analysis of 8 different electron transport chain (ETC) subunit mutants (3 missense and 5 RNAi-induced) in complexes I, II, and III. Results from this validation set provide insight into the contributions of individual complexes or subunits to primary mitochondrial dysfunction.
Organism: Caenorhabditis elegans
Platform: GPL200: [Celegans] Affymetrix C. elegans Genome Array
Citations:
  • Falk MJ, Zhang Z, Rosenjack JR, Nissim I et al. Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans. Mol Genet Metab 2008 Apr;93(4):388-97. PMID: 18178500
  • Dingley S, Polyak E, Lightfoot R, Ostrovsky J et al. Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans. Mitochondrion 2010 Mar;10(2):125-36. PMID: 19900588
Reference Series: GSE9897 Sample count: 10
Value type: transformed count Series published: 2008/02/14