Spinocerebellar ataxia type 1 knock-in model: cerebellum
Summary:
Analysis of cerebella from spinocerebellar ataxia type 1 (SCA1) knockin animals at an early symptomatic disease stage. SCA1 is a neurodegenerative disorder caused by expansion of a glutamine tract in ataxin-1. Results provide insight into the molecular basis of cerebellar pathogenesis in SCA1.
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