DataSet Record GDS3800: Expression Profiles Data Analysis Tools Sample Subsets
Title: von Hippel-Lindau (VHL) tumor suppressor protein deficiency effect on pancreatic islet cells
Cluster AnalysisGDS3800 Cluster Image
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Summary: Analysis of pancreatic islet cells deficient for the von Hippel-Lindau tumor suppressor protein from 18 to 26 wk-old animals. Loss of Vhlh in beta-cells leads to impaired glucose tolerance and to abnormal insulin secretion. Results provide insight into the role of Vhlh in pancreatic beta cells.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Zehetner J, Danzer C, Collins S, Eckhardt K et al. PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev 2008 Nov 15;22(22):3135-46. PMID: 19056893
Reference Series: GSE11484 Sample count: 6
Value type: count Series published: 2008/11/15