Analysis of liver from Sprague-Dawley males fed 1 of 6 diets: casein, casein+isoflavone (I), soy protein (SP), SP+I, casein+tofu, or tofu. Tofu and soy protein significantly lowered serum lipid levels. Results provide insight into the molecular mechanisms underlying reduced liver lipogenesis.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Takahashi Y, Konishi T. Tofu (soybean curd) lowers serum lipid levels and modulates hepatic gene expression involved in lipogenesis primarily through its protein, not isoflavone, component in rats. J Agric Food Chem 2011 Aug 24;59(16):8976-84. PMID: 21721588