DataSet Record GDS4186: Expression Profiles Data Analysis Tools Sample Subsets
Title: Lupus nephritis model response to sirolimus-induced mTOR inhibition (Mu11KsubA)
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Summary: Analysis of kidney from sirolimus-treated NZB/W F1 females at 36 and 42 weeks of age. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been efficacious in the NZB/W model of lupus nephritis. Results provide insight into role of the mTOR pathway in autoimmune lupus nephritis.
Organism: Mus musculus
Platform: GPL75: [Mu11KsubA] Affymetrix Murine 11K SubA Array
Citation:
  • Reddy PS, Legault HM, Sypek JP, Collins MJ et al. Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis. Arthritis Res Ther 2008;10(6):R127. PMID: 18980674
Reference Series: GSE12024 Sample count: 16
Value type: count Series published: 2008/11/21