Chronic hypoxia effect on dmDys model of Duchenne Muscular Dystrophy: single whole animal
Summary:
Analysis of 3-5 day-old dystrophin-deficient animals exposed to chronic hypoxia (CH) for 2 weeks. Respiratory muscle necrosis in late-stage DMD is associated with respiratory insufficiency and CH. Results provide insight into the effects of CH on dystrophin-deficient muscle in vivo.
Mosqueira M, Willmann G, Ruohola-Baker H, Khurana TS. Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD). PLoS One 2010 Oct 20;5(10):e13450. PMID: 20975992
