DataSet Record GDS4925: Expression Profiles Data Analysis Tools Sample Subsets
Title: Age-related hearing loss model: cochlea
Cluster AnalysisGDS4925 Cluster Image
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Summary: Analysis of cochlea from old CBA females and males with mild or severe age-related hearing loss (presbycusis). The CBA strain it loses its hearing progressively over its lifetime. Results provide insight into the molecular mechanisms underlying presbycusis.
Organism: Mus musculus
Platform: GPL339: [MOE430A] Affymetrix Mouse Expression 430A Array
Citations:
  • D'Souza M, Zhu X, Frisina RD. Novel approach to select genes from RMA normalized microarray data using functional hearing tests in aging mice. J Neurosci Methods 2008 Jun 30;171(2):279-87. PMID: 18455804
  • Tadros SF, D'Souza M, Zhu X, Frisina RD. Gene expression changes for antioxidants pathways in the mouse cochlea: relations to age-related hearing deficits. PLoS One 2014;9(2):e90279. PMID: 24587312
  • Pineros J, Zhu X, Ding B, Frisina RD. Connexins 30 and 43 expression changes in relation to age-related hearing loss. Hear Res 2024 Mar 15;444:108971. PMID: 38359484
Reference Series: GSE49543 Sample count: 41
Value type: transformed count Series published: 2013/08/06