Placenta response to maternal choline intake throughout the third trimester of pregnancy: dose response
Summary:
Analysis of placenta retrieved at delivery from healthy women who consumed up to 930mg choline/day throughout their third trimester of pregnancy. Results provide insight into the molecular mechanisms underlying the benefits of maternal choline supplementation on placental function.
GPL6480:
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Citation:
Jiang X, Bar HY, Yan J, Jones S et al. A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1). FASEB J 2013 Mar;27(3):1245-53. PMID: 23195033
