Hydrogen peroxide effect on superoxide dismutase 1-deficient yeast cells
Summary:
Analysis of superoxide dismutase 1 deficient cells treated with reactive oxygen species hydrogen peroxide (H2O2) for 20 minutes. Sod1 deletion in yeast is known to cause extensive oxidative damage. Results provide insight into the molecular basis of Sod1’s role in oxidative stress resistance.
Tsang CK, Liu Y, Thomas J, Zhang Y et al. Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun 2014 Mar 19;5:3446. PMID: 24647101