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    CTAGE8 CTAGE family member 8 [ Homo sapiens (human) ]

    Gene ID: 100142659, updated on 17-Sep-2024

    Summary

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    Official Symbol
    CTAGE8provided by HGNC
    Official Full Name
    CTAGE family member 8provided by HGNC
    Primary source
    HGNC:HGNC:37294
    See related
    Ensembl:ENSG00000289604 AllianceGenome:HGNC:37294
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CTAGE4
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein secretion; and vesicle cargo loading. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum exit site and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CTAGE8 in Genome Data Viewer
    Location:
    7q35
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (144266674..144269288, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143963767..143966381, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ARHGEF35 antisense RNA 1 Neighboring gene OR2A1 antisense RNA 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:143947746-143948246 Neighboring gene olfactory receptor family 2 subfamily A member 20 pseudogene Neighboring gene Rho guanine nucleotide exchange factor 34, pseudogene Neighboring gene olfactory receptor family 2 subfamily A member 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:143981368-143982251 Neighboring gene olfactory receptor family 2 subfamily A member 9 pseudogene Neighboring gene olfactory receptor family 2 subfamily A member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DNA sequence of human chromosome 7. Hillier LW, et al. Nature, 2003 Jul 10. PMID 12853948
    2. Toward a complete human genome sequence. Sanger Center, et al. Genome Res, 1998 Nov. PMID 9847074
    3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Brandenberger R, et al. Nat Biotechnol, 2004 Jun. PMID 15146197
    4. Architecture of the human interactome defines protein communities and disease networks. Huttlin EL, et al. Nature, 2017 May 25. PMID 28514442, Free PMC Article
    5. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Clone Names

    • FLJ77176

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle cargo loading IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cTAGE family member 8
    Names
    CTAGE family, member 4 pseudogene
    Cutaneous T-cell lymphoma-associated antigen 8
    Protein cTAGE-4
    Protein cTAGE-8
    cTAGE family member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278507.2 → NP_001265436.1  cTAGE family member 8

      See identical proteins and their annotated locations for NP_001265436.1

      Status: VALIDATED

      Source sequence(s)
      AC004889
      Consensus CDS
      CCDS64791.1
      UniProtKB/Swiss-Prot
      P0CG41
      UniProtKB/TrEMBL
      A0A5F9ZHA4
      Related
      ENSP00000417289.1, ENST00000487179.2
      Conserved Domains (3) summary
      pfam10211
      Location:157 → 229
      Ax_dynein_light; Axonemal dynein light chain
      pfam14662
      Location:107 → 298
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      pfam15233
      Location:338 → 445
      SYCE1; Synaptonemal complex central element protein 1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      144266674..144269288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_018654715.1 Reference GRCh38.p14 PATCHES

      Range
      221268..223882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CG41.1 GenPept UniProtKB/Swiss-Prot:P0CG41

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials