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    SCN1A sodium voltage-gated channel alpha subunit 1 [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

    Gene ID: 111523510, updated on 15-Mar-2024

    Summary

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    Gene symbol
    SCN1A
    Gene description
    sodium voltage-gated channel alpha subunit 1
    See related
    Ensembl:ENSPTEG00000034476
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Piliocolobus tephrosceles
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
    Orthologs
    human mouse all
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    Genomic context

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    See SCN1A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    102 current ASM277652v3 (GCF_002776525.3) 11 NC_045444.1 (51871429..51952960, complement)
    100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019318164.1 (1007789..1166551, complement)

    Chromosome 11 - NC_045444.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 3 Neighboring gene tetratricopeptide repeat domain 21B Neighboring gene uncharacterized LOC111523506 Neighboring gene sodium voltage-gated channel alpha subunit 9 Neighboring gene small nucleolar RNA U13 Neighboring gene sodium voltage-gated channel alpha subunit 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 1 subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM277652v3

    Genomic

    1. NC_045444.1 Reference ASM277652v3

      Range
      51871429..51952960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031936565.1 → XP_031792425.1  sodium channel protein type 1 subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A8C9IHG6, A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1484 → 1536
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1217 → 1492
      Ion_trans; Ion transport protein
      pfam06512
      Location:1006 → 1213
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:510 → 718
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1808 → 1855
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    2. XM_023188155.2 → XP_023043923.1  sodium channel protein type 1 subunit alpha isoform X7

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1462 → 1514
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1195 → 1470
      Ion_trans; Ion transport protein
      pfam06512
      Location:984 → 1191
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:499 → 683
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1778 → 1841
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    3. XM_026454143.1 → XP_026309928.1  sodium channel protein type 1 subunit alpha isoform X5

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1473 → 1525
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1206 → 1481
      Ion_trans; Ion transport protein
      pfam06512
      Location:995 → 1202
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:499 → 694
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1789 → 1852
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    4. XM_023188156.2 → XP_023043924.1  sodium channel protein type 1 subunit alpha isoform X8

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1423 → 1475
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1156 → 1431
      Ion_trans; Ion transport protein
      pfam06512
      Location:945 → 1152
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:509 → 644
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1739 → 1802
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    5. XM_031936569.1 → XP_031792429.1  sodium channel protein type 1 subunit alpha isoform X6

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1455 → 1507
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1188 → 1463
      Ion_trans; Ion transport protein
      pfam06512
      Location:977 → 1184
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:509 → 689
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1779 → 1826
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    6. XM_031936567.1 → XP_031792427.1  sodium channel protein type 1 subunit alpha isoform X3

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1472 → 1524
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1205 → 1480
      Ion_trans; Ion transport protein
      pfam06512
      Location:994 → 1201
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:509 → 706
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1796 → 1843
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    7. XM_031936568.1 → XP_031792428.1  sodium channel protein type 1 subunit alpha isoform X4

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1456 → 1508
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1189 → 1464
      Ion_trans; Ion transport protein
      pfam06512
      Location:978 → 1185
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:510 → 690
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1780 → 1827
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    8. XM_031936566.1 → XP_031792426.1  sodium channel protein type 1 subunit alpha isoform X2

      UniProtKB/TrEMBL
      A0A8C9IHK5
      Conserved Domains (5) summary
      cd13433
      Location:1473 → 1525
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1206 → 1481
      Ion_trans; Ion transport protein
      pfam06512
      Location:995 → 1202
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:510 → 707
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1797 → 1844
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
    Heading Accession and Version

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