opn1mw1 opsin 1 (cone pigments), medium-wave-sensitive, 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: opn1mw1provided by ZNC
Official Full Name: opsin 1 (cone pigments), medium-wave-sensitive, 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-990604-42
See related: Ensembl:ENSDARG00000097008 AllianceGenome:ZFIN:ZDB-GENE-990604-42
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: RH2-1; rh2.1; zfgr1; grops1
Summary: Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within signal transduction and visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including endocrine system; heart; integument; photoreceptor cell; and visual system. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (41181882..41183823)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (41184346..41186287)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Six6b and six7 govern expression of the SWS2 and RH2 opsins responsible for middle-wavelength sensitivity.
Title: Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled photoreceptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables photoreceptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in cellular response to light stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in phototransduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phototransduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within visual perception	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in photoreceptor outer segment	IBA Inferred from Biological aspect of Ancestor more info
located_in photoreceptor outer segment	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: green-sensitive opsin-1

Names: green cone photoreceptor pigment 1; opsin RH2-1; opsin-1, medium-wave-sensitive 1; rhodopsin-like-2.1 cone opsin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131253.2 → NP_571328.2 green-sensitive opsin-1

See identical proteins and their annotated locations for NP_571328.2

Status: PROVISIONAL

Source sequence(s)

BC060896

UniProtKB/Swiss-Prot

Q8AYM9, Q9W6A5

UniProtKB/TrEMBL

A0A0N9NXZ8

Related

ENSDARP00000001158.5, ENSDART00000002046.8

Conserved Domains (3) summary

pfam00001
Location:55 → 306

7tm_1; 7 transmembrane receptor (rhodopsin family)

pfam10413
Location:2 → 37

Rhodopsin_N; Amino terminal of the G-protein receptor rhodopsin

cl21561
Location:45 → 222

7tm_4; Olfactory receptor