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    hfm1 helicase for meiosis 1 [ Danio rerio (zebrafish) ]

    Gene ID: 557052, updated on 12-Sep-2024

    Summary

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    Official Symbol
    hfm1provided by ZNC
    Official Full Name
    helicase for meiosis 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061207-43
    See related
    AllianceGenome:ZFIN:ZDB-GENE-061207-43
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-83f14.5
    Summary
    Predicted to enable DNA helicase activity. Predicted to be involved in resolution of meiotic recombination intermediates. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 9. Orthologous to human HFM1 (helicase for meiosis 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See hfm1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (22531218..22567297)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (22875546..22910172)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 8 VRAC subunit Da Neighboring gene zinc finger protein 644a Neighboring gene transcription factor Sox-14 Neighboring gene claudin 18 Neighboring gene septin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in resolution of meiotic recombination intermediates IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    probable ATP-dependent DNA helicase HFM1
    Names
    HFM1, ATP-dependent DNA helicase homolog
    XP_021322847.2
    XP_068069990.1
    XP_068069991.1
    XP_068069993.1
    XP_068069994.1
    XP_068069997.1
    XP_068069999.1
    XP_068070006.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      22531218..22567297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021467172.2 → XP_021322847.2  probable ATP-dependent DNA helicase HFM1 isoform X1

    2. XM_068213890.1 → XP_068069991.1  probable ATP-dependent DNA helicase HFM1 isoform X2

    3. XM_068213896.1 → XP_068069997.1  probable ATP-dependent DNA helicase HFM1 isoform X5

    4. XM_068213905.1 → XP_068070006.1  probable ATP-dependent DNA helicase HFM1 isoform X7

    5. XM_068213898.1 → XP_068069999.1  probable ATP-dependent DNA helicase HFM1 isoform X6

    6. XM_068213893.1 → XP_068069994.1  probable ATP-dependent DNA helicase HFM1 isoform X4

    7. XM_068213892.1 → XP_068069993.1  probable ATP-dependent DNA helicase HFM1 isoform X3

    8. XM_068213889.1 → XP_068069990.1  probable ATP-dependent DNA helicase HFM1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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