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    nrbp2a nuclear receptor binding protein 2a [ Danio rerio (zebrafish) ]

    Gene ID: 564177, updated on 2-Nov-2024

    Summary

    Official Symbol
    nrbp2aprovided by ZNC
    Official Full Name
    nuclear receptor binding protein 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070713-4
    See related
    Ensembl:ENSDARG00000032951 AllianceGenome:ZFIN:ZDB-GENE-070713-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nrbp2
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and neuron differentiation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and endomembrane system. Orthologous to human NRBP2 (nuclear receptor binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See nrbp2a in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (32673366..32738549, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (32690271..32755391, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene chemokine (C-C motif) receptor 9a Neighboring gene small nucleolar RNA SNORA57 Neighboring gene small nucleolar RNA SNORA57 Neighboring gene poly-U binding splicing factor a Neighboring gene uncharacterized LOC101887149 Neighboring gene kelch-like family member 18 Neighboring gene beaded filament structural protein 2, phakinin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    nuclear receptor-binding protein 2
    Names
    nuclear receptor binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      32673366..32738549 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021467601.2XP_021323276.1  nuclear receptor-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PLZ2
      Conserved Domains (1) summary
      cl21453
      Location:43301
      PKc_like; Protein Kinases, catalytic domain
    2. XM_001920637.7XP_001920672.2  nuclear receptor-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QKH0
      Related
      ENSDARP00000113223.1, ENSDART00000135293.2
      Conserved Domains (2) summary
      smart00220
      Location:53300
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:43304
      PKc_like; Protein Kinases, catalytic domain