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    tent4b terminal nucleotidyltransferase 4B [ Danio rerio (zebrafish) ]

    Gene ID: 568678, updated on 17-Sep-2024

    Summary

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    Official Symbol
    tent4bprovided by ZNC
    Official Full Name
    terminal nucleotidyltransferase 4Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041021-2
    See related
    Ensembl:ENSDARG00000060071 AllianceGenome:ZFIN:ZDB-GENE-041021-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    papd5; polsl
    Summary
    Predicted to enable RNA binding activity and polynucleotide adenylyltransferase activity. Predicted to act upstream of or within RNA polyadenylation. Is expressed in ovary and testis. Orthologous to human TENT4B (terminal nucleotidyltransferase 4B). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See tent4b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (37861250..37895949, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (37589992..37624691, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene bromodomain containing 7 Neighboring gene adenylate cyclase 7 Neighboring gene HEAT repeat containing 3 Neighboring gene uncharacterized LOC137496184

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos. Chang H, et al. Mol Cell, 2018 Apr 5. PMID 29625039
    2. Hen1 is required for oocyte development and piRNA stability in zebrafish. Kamminga LM, et al. EMBO J, 2010 Nov 3. PMID 20859253, Free PMC Article
    3. Organization of Iroquois genes in fish. Dildrop R, et al. Dev Genes Evol, 2004 Jun. PMID 15133664
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(A) RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    terminal nucleotidyltransferase 4B
    Names
    PAP associated domain containing 5
    TUTase3
    polymerase (DNA directed) sigma like
    NP_001313625.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326696.1 → NP_001313625.1  terminal nucleotidyltransferase 4B

      Status: VALIDATED

      Source sequence(s)
      BX663605
      UniProtKB/TrEMBL
      A0A1D6UPT1, A0A8M1P2W0
      Related
      ENSDARP00000078717.6, ENSDART00000084282.7
      Conserved Domains (2) summary
      cd05402
      Location:188 → 298
      NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
      pfam03828
      Location:356 → 416
      PAP_assoc; Cid1 family poly A polymerase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      37861250..37895949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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