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    naa60 N-alpha-acetyltransferase 60, NatF catalytic subunit [ Danio rerio (zebrafish) ]

    Gene ID: 570640, updated on 18-Sep-2024

    Summary

    Official Symbol
    naa60provided by ZNC
    Official Full Name
    N-alpha-acetyltransferase 60, NatF catalytic subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-143
    See related
    Ensembl:ENSDARG00000061185 AllianceGenome:ZFIN:ZDB-GENE-041111-143
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    HAT4; NatF; nat15; im:7141641; zgc:163109
    Summary
    Predicted to enable H4 histone acetyltransferase activity; peptide alpha-N-acetyltransferase activity; and protein homodimerization activity. Predicted to be involved in several processes, including chromosome segregation; nucleosome assembly; and protein acetylation. Predicted to act upstream of or within chromatin organization. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Orthologous to human NAA60 (N-alpha-acetyltransferase 60, NatF catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See naa60 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (27786687..27796349)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (27655845..27665507)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene enoyl-CoA delta isomerase 1 Neighboring gene deoxyribonuclease I Neighboring gene calcium regulated heat stable protein 1 Neighboring gene 4-aminobutyrate aminotransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4 acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptide alpha-N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide alpha-N-acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal peptidyl-methionine acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in N-terminal protein amino acid acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nucleosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 60
    Names
    N-acetyltransferase 15 (GCN5-related, putative)
    N-alpha-acetyltransferase F
    histone acetyltransferase type B protein 4
    natF catalytic subunit
    NP_001076341.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082872.1NP_001076341.1  N-alpha-acetyltransferase 60

      See identical proteins and their annotated locations for NP_001076341.1

      Status: PROVISIONAL

      Source sequence(s)
      BC134236
      UniProtKB/Swiss-Prot
      A3KPA3
      Related
      ENSDARP00000081428.4, ENSDART00000086994.5
      Conserved Domains (2) summary
      COG0456
      Location:20166
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:79156
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      27786687..27796349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)