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    IA-2 IA-2 protein tyrosine phosphatase [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 663427, updated on 10-May-2024

    Summary

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    Gene symbol
    IA-2
    Gene description
    IA-2 protein tyrosine phosphatase
    Locus tag
    TcasGA2_TC012616
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Orthologs
    fruit fly all
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    Genomic context

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    See IA-2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 2 NC_087395.1 (22716239..22723819)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG9 NC_007424.3 (12189869..12197491)

    Chromosome 2 - NC_087395.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Rho GTPase activating protein at 19D Neighboring gene Post-GPI attachment to proteins 3 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene no extended memory Neighboring gene FGGY carbohydrate kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in secretory granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase N2
    Names
    AUGUSTUS-3.0.2_12616
    GLEAN_12616
    Receptor-type tyrosine-protein phosphatase N2-like Protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087395.1 Reference icTriCast1.1 Primary Assembly

      Range
      22716239..22723819
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008199879.3 → XP_008198101.1  receptor-type tyrosine-protein phosphatase N2

      See identical proteins and their annotated locations for XP_008198101.1

      UniProtKB/TrEMBL
      D6WZ66
      Conserved Domains (3) summary
      smart00194
      Location:719 → 978
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:746 → 978
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam11548
      Location:496 → 581
      Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
    Nucleotide Protein Strain
    Heading Accession and Version

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