6TED: Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1

PDB ID: 6TEDDownload
MMDB ID: 190384
PDB Deposition Date: 2019/11/11
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
synthetic construct
Similar Structures:
Biological Unit for 6TED: 24-meric; determined by author and by software (PISA)
Molecular Components in 6TED
Label Count Molecule
Proteins (21 molecules)
1
DNA-directed RNA Polymerase Subunit
Molecule annotation
1
DNA-directed RNA Polymerase Subunit Beta
Molecule annotation
1
RNA Polymerase II Subunit C
Molecule annotation
1
RNA Polymerase II Subunit D
Molecule annotation
1
RNA Polymerase II Subunit E
Molecule annotation
1
RNA Polymerase II Subunit F
Molecule annotation
1
RNA Polymerase II Subunit G
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc3
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb9
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
1
Transcription Elongation Factor Spt6
Molecule annotation
1
RNA Polymerase-associated Protein Ctr9 Homolog
Molecule annotation
1
RNA Polymerase-associated Protein Rtf1 Homolog
Molecule annotation
1
RNA Polymerase-associated Protein Leo1
Molecule annotation
1
RNA Polymerase Ii-associated Factor 1 Homolog
Molecule annotation
1
WD Repeat-containing Protein 61
Molecule annotation
1
Parafibromin
Molecule annotation
1
Transcription Elongation Factor Spt4
Molecule annotation
1
Transcription Elongation Factor Spt5
Molecule annotation
Nucleotides(3 molecules)
1
DNA (37-mer)
Molecule annotation
1
RNA (5'-r(p*up*ap*ap*cp*cp*gp*gp*ap*gp*ap*gp*gp*gp*ap*ap*cp*cp*cp*ap*cp*u)-3')
Molecule annotation
1
Template DNA
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
9
1
* Click molecule labels to explore molecular sequence information.

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