5SXI: Crystal Structure of PI3Kalpha in complex with fragment 13

PDB ID: 5SXIDownload
MMDB ID: 182250
PDB Deposition Date: 2016/8/9
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5SXI: dimeric; determined by author and by software (PISA)
Molecular Components in 5SXI
Label Count Molecule
Proteins (2 molecules)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Alpha Isoform
(Gene symbol: PIK3CA)
Molecule annotation
1
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha
(Gene symbol: PIK3R1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
trans-cyclohexane-1,4-dioltrans-cyclohexane-1,4-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303