4BGQ: Crystal structure of the human CDKL5 kinase domain

PDB ID: 4BGQDownload
MMDB ID: 109808
PDB Deposition Date: 2013/3/28
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4BGQ: monomeric; determined by author and by software (PISA)
Molecular Components in 4BGQ
Label Count Molecule
Protein (1 molecule)
1
Cyclin-dependent Kinase-like 5
(Gene symbol: CDKL5)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
SODIUM IONSODIUM ION
2
1
[4-({4-[(3-cyclopentyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile[4-({4-[(3-cyclopentyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303