6CK6: Crystal Structure of Mnk2-D228G in complex with Inhibitor

PDB ID: 6CK6Download
MMDB ID: 161894
PDB Deposition Date: 2018/2/27
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.32  Å
Source Organism:
Similar Structures:
Biological Unit for 6CK6: monomeric; determined by author and by software (PISA)
Molecular Components in 6CK6
Label Count Molecule
Protein (1 molecule)
1
MAP Kinase-interacting Serine/threonine-protein Kinase 2
(Gene symbol: MKNK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303