5J8I: Crystal structure of TL11-113 bound to TAK1-TAB1

PDB ID: 5J8IDownload
MMDB ID: 147303
PDB Deposition Date: 2016/4/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.404  Å
Source Organism:
Similar Structures:
Biological Unit for 5J8I: monomeric; determined by author and by software (PISA)
Molecular Components in 5J8I
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase Kinase Kinase 7/tgf-beta-activated Kinase 1 and Map3k7-binding Protein 1 Chimera
(Gene symbol: MAP3K7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamideN-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303