2FOI: Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase

PDB ID: 2FOIDownload
MMDB ID: 43771
PDB Deposition Date: 2006/1/13
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2FOI: tetrameric; determined by author and by software (PISA)
Molecular Components in 2FOI
Label Count Molecule
Proteins (4 molecules)
2
Enoyl-acyl Carrier Reductase
Molecule annotation
2
Enoyl-acyl Carrier Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
2
4-(2,4-DICHLOROPHENOXY)-2'-METHYLBIPHENYL-3-OL4-(2,4-DICHLOROPHENOXY)-2'-METHYLBIPHENYL-3-OL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303