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The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation[LIGASE]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide[LIGASE]
View in iCn3D Similar StructuresProteinsConserved DomainsPubChem Compound
Siah1 bound to synthetic peptide (ACE)KLRPVAMVRP(PRK)VR[LIGASE/LIGASE INHIBITOR]
Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR[LIGASE/LIGASE INHIBITOR]
Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR[LIGASE/LIGASE INHIBITOR]
Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP[LIGASE]
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