6H0F: Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2)

PDB ID: 6H0FDownload
MMDB ID: 174487
PDB Deposition Date: 2018/7/9
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 3.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6H0F: trimeric; determined by author
Molecular Components in 6H0F
Label Count Molecule
Proteins (3 molecules)
1
DNA Damage-binding Protein 1,dna Damage-binding Protein 1,dna Damage-binding Protein 1,dna Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
1
DNA-binding Protein Ikaros
(Gene symbol: IKZF1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
S-PomalidomideS-Pomalidomide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303