8R6Q: Co-crystal structure of PD-L1 with low molecular weight inhibitor

PDB ID: 8R6QDownload
MMDB ID: 241439
PDB Deposition Date: 2023/11/22
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 8R6Q: dimeric; determined by author and by software (PISA)
Molecular Components in 8R6Q
Label Count Molecule
Proteins (2 molecules)
2
Programmed Cell Death 1 Ligand 1
(Gene symbol: CD274)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(3~{R})-1-[[4-[2-chloranyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]-2-methoxy-phenyl]methyl]-~{N}-(2-hydroxyethyl)pyrrolidine-3-carboxamide(3~{R})-1-[[4-[2-chloranyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]-2-methoxy-phenyl]methyl]-~{N}-(2-hydroxyethyl)pyrrolidine-3-carboxamide
2
2
CHLORIDE IONCHLORIDE ION
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303