8C6J: Human spliceosomal PM5 C* complex

PDB ID: 8C6JDownload
MMDB ID: 232751
PDB Deposition Date: 2023/1/12
Updated in MMDB: 2023/07
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8C6J: 63-meric; determined by author and by software
Molecular Components in 8C6J
Label Count Molecule
Proteins (58 molecules)
1
Splicing Factor Ess-2 Homolog
Molecule annotation
1
Eukaryotic Initiation Factor 4a-iii
Molecule annotation
1
RNA-binding Protein 8A
Molecule annotation
1
Protein Mago Nashi Homolog
Molecule annotation
1
Pre-mrna-processing-splicing Factor 8
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 200 KDA Helicase
Molecule annotation
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 3
Molecule annotation
1
Probable Atp-dependent RNA Helicase Ddx41
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase E
Molecule annotation
1
Protein Fam50a
Molecule annotation
1
Pre-mrna-splicing Factor Isy1 Homolog
Molecule annotation
1
Nitric Oxide Synthase-interacting Protein
Molecule annotation
1
Splicing Factor C9orf78
Molecule annotation
1
Prkr-interacting Protein 1
Molecule annotation
1
Splicing Factor Cactin
Molecule annotation
1
Protein Fam32a
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22 Homolog
Molecule annotation
1
Pleiotropic Regulator 1
Molecule annotation
1
SNW Domain-containing Protein 1
Molecule annotation
1
Protein Bud31 Homolog
Molecule annotation
1
Pre-mrna-splicing Factor Rbm22
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
Molecule annotation
1
Cell Division Cycle 5-like Protein
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 2
Molecule annotation
1
Crooked Neck-like Protein 1
Molecule annotation
1
Pre-mrna-splicing Factor Syf1
Molecule annotation
1
Intron-binding Protein Aquarius
Molecule annotation
1
Atp-dependent RNA Helicase Dhx8
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein A'
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein B''
Molecule annotation
1
Nf-kappa-b-activating Protein
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Proteins B and B'
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3
Molecule annotation
2
Small Nuclear Ribonucleoprotein E
Molecule annotation
2
Small Nuclear Ribonucleoprotein F
Molecule annotation
2
Small Nuclear Ribonucleoprotein G
Molecule annotation
1
Pre-mrna-splicing Factor Slu7
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 1
Molecule annotation
1
Sting ER Exit Protein
Molecule annotation
1
Pre-mrna-processing Factor 17
Molecule annotation
1
Pre-mrna-splicing Factor Spf27
Molecule annotation
4
Pre-mrna-processing Factor 19
Molecule annotation
1
Pre-mrna-splicing Factor Syf2
Molecule annotation
1
Splicing Regulator Sde2
Molecule annotation
Nucleotides(5 molecules)
1
U2 Snrna
Molecule annotation
1
U5 Snrna
Molecule annotation
1
U6 Snrna
Molecule annotation
1
PM5 5' Exon
Molecule annotation
1
PM5 Intron
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
POTASSIUM IONPOTASSIUM ION
2
7
MAGNESIUM IONMAGNESIUM ION
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
1
INOSITOL HEXAKISPHOSPHATEINOSITOL HEXAKISPHOSPHATE
5
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
6
6
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303