4YUR: Crystal Structure of Plk4 Kinase Domain Bound to Centrinone

PDB ID: 4YURDownload
MMDB ID: 130147
PDB Deposition Date: 2015/3/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 4YUR: monomeric; determined by author and by software (PISA)
Molecular Components in 4YUR
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Plk4
(Gene symbol: PLK4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-({2-fluoro-4-[(2-fluoro-3-nitrobenzyl)sulfonyl]phenyl}sulfanyl)-5-methoxy-N-(3-methyl-1H-pyrazol-5-yl)-6-(morpholin-4-yl)pyrimidin-4-amine2-({2-fluoro-4-[(2-fluoro-3-nitrobenzyl)sulfonyl]phenyl}sulfanyl)-5-methoxy-N-(3-methyl-1H-pyrazol-5-yl)-6-(morpholin-4-yl)pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303