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5LIW:
Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK319
PDB ID:
5LIW
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MMDB ID:
141444
PDB Deposition Date:
2016/7/15
Updated in MMDB:
2016/11
Experimental Method:
x-ray diffraction
Resolution:
1.75 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 5LIW: monomeric; determined by author and by software (PISA)
Molecular Components in 5LIW
Label
Count
Molecule
Protein (1 molecule)
X
1
Aldo-keto Reductase Family 1 Member B10
(Gene symbol:
AKR1B10
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
{2-[(4-bromo-2,3,5,6-tetrafluorobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid
3
1
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303