5TWN: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide

PDB ID: 5TWNDownload
MMDB ID: 148430
PDB Deposition Date: 2016/11/14
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 3.04  Å
Source Organism:
Similar Structures:
Biological Unit for 5TWN: monomeric; determined by author
Molecular Components in 5TWN
Label Count Molecule
Protein (1 molecule)
1
Ns5b RNA- Dependent RNA Polymerase
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
(2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid(2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid
2
6
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303