2EWY: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor

PDB ID: 2EWYDownload
MMDB ID: 42704
PDB Deposition Date: 2005/11/7
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2EWY: monomeric; determined by author and by software (PQS)
Molecular Components in 2EWY
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 2
(Gene symbol: BACE2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHYLBENZYL)AMINO]PROPYL}DIBENZO[B,F]OXEPINE-10-CARBOXAMIDEN-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHYLBENZYL)AMINO]PROPYL}DIBENZO[B,F]OXEPINE-10-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303