6TTU: Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2

PDB ID: 6TTUDownload
MMDB ID: 184155
PDB Deposition Date: 2019/12/30
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6TTU: octameric; determined by author and by software (PISA)
Molecular Components in 6TTU
Label Count Molecule
Proteins (8 molecules)
1
F-box/wd Repeat-containing Protein 1A
(Gene symbol: BTRC)
Molecule annotation
1
S-phase Kinase-associated Protein 1
(Gene symbol: SKP1)
Molecule annotation
1
Cullin-1
(Gene symbol: CUL1)
Molecule annotation
1
Nedd8
(Gene symbol: NEDD8)
Molecule annotation
1
E3 Ubiquitin-protein Ligase Rbx1
(Gene symbol: RBX1)
Molecule annotation
1
Ubiquitin-conjugating Enzyme E2 D2
(Gene symbol: UBE2D2)
Molecule annotation
1
Polyubiquitin-c
(Gene symbol: UBC)
Molecule annotation
1
Cys-lys-lys-ala-arg-his-asp-sep-gly
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303