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7SYR: Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt)

PDB ID:

MMDB ID:

218429

PDB Deposition Date:

2021/11/25

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

3.6 Å

Source Organism:

Hepatitis C virus (isolate 1)▼

Taxonomy	Molecule
Hepatitis C virus (isolate 1)	z
Oryctolagus cuniculus	2, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h , i, n
Homo sapiens	A, j

Similar Structures:

Biological Unit for 7SYR: 39-meric; determined by author

Molecular Components in 7SYR
Label	Count	Molecule
Proteins (36 molecules)
A	1	Eukaryotic Translation Initiation Factor 1A, X-chromosomal
B	1	US2 (Sa)
C	1	ES1
D	1	US5
E	1	US3
F	1	ES4 (S4 X Isoform)
G	1	US7
H	1	ES6
I	1	ES7
J	1	ES8
K	1	US4
L	1	Es10
M	1	Us17
N	1	Es12
O	1	Us15
P	1	Us11
Q	1	Us19
R	1	US9
S	1	Es17
T	1	Us13
U	1	Es19
V	1	Us10
W	1	Es21
X	1	US8
Y	1	Us12
Z	1	Es24
a	1	Es25
b	1	Es26
c	1	Es27
d	1	Es28
e	1	Us14
f	1	Es30
g	1	Es31
h	1	Receptor for Activated C Kinase 1 (Rack1)
j	1	Eukaryotic Translation Initiation Factor 2 Subunit 1
n	1	El41
Nucleotides(3 molecules)
2	1	18S rRNA
i	1	Met-trna-i-met
z	1	HCV Ires
Chemical and Non-standard biopolymers (1 molecule)
1	1	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB