3OW2: Crystal Structure Of Enhanced Macrolide Bound To 50s Ribosomal Subunit

PDB ID: 3OW2Download
MMDB ID: 100627
PDB Deposition Date: 2010/9/17
Updated in MMDB: 2012/06
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3OW2: 30-meric; determined by author
Molecular Components in 3OW2
Label Count Molecule
Proteins (28 molecules)
1
50S Ribosomal Protein L2P
(Gene symbol: RR_RS11185)
Molecule annotation
1
50S Ribosomal Protein L3P
(Gene symbol: rpl3p)
Molecule annotation
1
50S Ribosomal Protein L4P
(Gene symbol: rpl4p)
Molecule annotation
1
50S Ribosomal Protein L5P
(Gene symbol: RR_RS11135)
Molecule annotation
1
50S Ribosomal Protein L6P
(Gene symbol: RR_RS11120)
Molecule annotation
1
50S Ribosomal Protein L7ae
(Gene symbol: RR_RS04485)
Molecule annotation
1
50S Ribosomal Protein L10e
(Gene symbol: RR_RS10280)
Molecule annotation
1
50S Ribosomal Protein L10e
Molecule annotation
1
50S Ribosomal Protein L13p
(Gene symbol: RR_RS04320)
Molecule annotation
1
50S Ribosomal Protein L14p
(Gene symbol: RR_RS11150)
Molecule annotation
1
50S Ribosomal Protein L15p
(Gene symbol: RR_RS11090)
Molecule annotation
1
50S Ribosomal Protein L15e
Molecule annotation
1
50S Ribosomal Protein L18p
(Gene symbol: RR_RS11105)
Molecule annotation
1
50S Ribosomal Protein L18e
(Gene symbol: RR_RS04315)
Molecule annotation
1
50S Ribosomal Protein L19e
(Gene symbol: RR_RS11110)
Molecule annotation
1
50S Ribosomal Protein L21e
(Gene symbol: RR_RS05195)
Molecule annotation
1
50S Ribosomal Protein L22p
(Gene symbol: RR_RS11175)
Molecule annotation
1
50S Ribosomal Protein L23p
(Gene symbol: RR_RS11190)
Molecule annotation
1
50S Ribosomal Protein L24p
(Gene symbol: RR_RS11145)
Molecule annotation
1
50S Ribosomal Protein L24e
(Gene symbol: RR_RS04495)
Molecule annotation
1
50S Ribosomal Protein L29p
(Gene symbol: rpmC)
Molecule annotation
1
50S Ribosomal Protein L30p
(Gene symbol: rpmD)
Molecule annotation
1
50S Ribosomal Protein L31e
(Gene symbol: RR_RS17815)
Molecule annotation
1
50S Ribosomal Protein L32e
(Gene symbol: RR_RS11115)
Molecule annotation
1
50S Ribosomal Protein L37ae
Molecule annotation
1
50S Ribosomal Protein L37e
Molecule annotation
1
50S Ribosomal Protein L39e
(Gene symbol: RR_RS17810)
Molecule annotation
1
50S Ribosomal Protein L44e
(Gene symbol: RR_RS19595)
Molecule annotation
Nucleotides(2 molecules)
1
23S Ribosomal RNA
Molecule annotation
1
5S Ribosomal RNA
Molecule annotation
Chemicals and Non-standard biopolymers (204 molecules)
1
61
Magnesium IonMagnesium Ion
2
1
Potassium IonPotassium Ion
3
26
Sodium IonSodium Ion
4
13
Chloride IonChloride Ion
5
98
Strontium IonStrontium Ion
6
1
(2r,3s,4r,5r,8r,10r,11r,12s,13s,14r)-2-Ethyl-3,4,10-Trihydroxy-3,5,6,8,10,12,14-Heptamethyl-15-Oxo-11-[(3,4,6-Trideoxy-3-{[3-(1-{(1s,2r)-1-(Fluoromethyl)-2-Hydroxy-2-[4-(Methylsulfonyl)phenyl]ethyl}-1h-1,2,3-Triazol-4-Yl)propyl](Methyl)amino}-Beta-D-Xylo-Hexopyranosyl)oxy]-1-Oxa-6-Azacyclopentadecan-13-Yl 2,6-Dideoxy-3-C-Methyl-3-O-Methyl-Alpha-L-Ribo-Hexopyranoside(2r,3s,4r,5r,8r,10r,11r,12s,13s,14r)-2-Ethyl-3,4,10-Trihydroxy-3,5,6,8,10,12,14-Heptamethyl-15-Oxo-11-[(3,4,6-Trideoxy-3-{[3-(1-{(1s,2r)-1-(Fluoromethyl)-2-Hydroxy-2-[4-(Methylsulfonyl)phenyl]ethyl}-1h-1,2,3-Triazol-4-Yl)propyl](Methyl)amino}-Beta-D-Xylo-Hexopyranosyl)oxy]-1-Oxa-6-Azacyclopentadecan-13-Yl 2,6-Dideoxy-3-C-Methyl-3-O-Methyl-Alpha-L-Ribo-Hexopyranoside
7
4
Cadmium IonCadmium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303