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3VRY:
Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane
PDB ID:
3VRY
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MMDB ID:
109508
PDB Deposition Date:
2012/4/21
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.481 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 3VRY: monomeric; determined by author and by software (PISA)
Molecular Components in 3VRY
Label
Count
Molecule
Protein (1 molecule)
A
1
Tyrosine-protein Kinase HCK
(Gene symbol:
HCK
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane
2
1
CHLORIDE ION
3
2
CALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303