ReferenceReason for exclusion
Abe 19822No multivariate analysis. Addresses a different question. An investigation into how the behaviours manifested at 3 years of age have changed after 5 years’ follow-up
Abend 20113Univariate analysis only. Retrospective analysis of children identified from a prospective paediatric stroke registry to define the incidence of seizures as presenting symptom of arterial ischemic stroke
Adelow 20097No multivariate analysis
Akhtar 200214People previously diagnosed with epilepsy underwent ECG to determine how many children may have cardiovascular anomalies. Authors only present the number of people with possible alternative diagnoses to epilepsy. No multivariate analysis
Alam 201218Narrative literature review
Altunbasak 2007202-year prognosis of epilepsy
An 201025Logistic regression only used for predictors of prognosis
Anderson 198926Addresses a different question
Annegers 200028Univariate analysis
Annegers 199829No multivariate analysis
Annegers 198730Addresses a different question. Prognostic factors of unprovoked seizures after febrile convulsions
Apakama 200634Addresses a different question. Video monitoring in children referred for an outpatient EEG
Arango 201236No multivariate analysis
Arndt 201638Narrative review. No extractable data
Attumalil 201142Variables in the multivariate analysis were only looking at birth and neonatal aspects. No predictors of interest to our review were included
Austin 201544Addresses a different question. The variables included in the multivariate analysis include parent variables, child behaviours problems and seizure occurrence, which are not predictors of interest to our review question
Austin 200145Addresses a different question. The variables included in the multivariate analysis are our outcomes of interest not the predictors
Austin 201146Addresses a different question. The variables included in the multivariate analysis include demographic, seizure risk factors and family risk factors, which are not predictors of interest to our review question
Bademosi 198950Case control study with no multivariate analysis
Berg 199864Addresses a different question. Looks at the influence of the onset of unprovoked seizures in the recurrence of seizures in children after febrile seizures
Berg 199665No multivariate analysis
Berg 199966Identification of differences between children with epilepsy with and without febrile seizures
Bergamo 201567Univariate analysis only
Bertelsen 201669Abstract only
Beslow 201371Addresses a different question. Risk factors for seizures and epilepsy in children. No multivariate analysis
Beslow 201072Addresses a different question. Features of children with intracerebral haemorrhage and predictors of short-term outcomes
Bessiso 199073No multivariate analysis
Betts 199274Addresses a different question
Bhattacharyya 201476Univariate analysis only
Bonkowsky 200979No multivariate analysis
Bosson 201483Addresses a different question. Risk of apnoea in patients with seizures. Multivariate analysis includes age, medicated in the field, seizure on PED arrival and seizure disorder
Bosson 201484Addresses a different question. Risk factors for apnoea not apnoea as a risk factor
Brown 199692Narrative review. No extractable data
Bye 199495Clinical description of complex partial seizures. No multivariate analysis
Bye 200096No multivariate analysis. Ten-year retrospective study of non-epileptic paroxysmal events in children
Canavese 201299Addresses a different question. Clinical and video-EEG-polymyographic study of paroxysmal non-epileptic motor events
Canpolat 2014102No multivariate analysis
Cansu 2007103No association of symptoms. Not clear if patients had paroxysmal events and one of the predictors or not
Caplan 2004104Addresses a different question. Looking at the role of cognition, language, seizure and demographic variables in the psychopathology of complex partial seizures
Caraballo 2003105Univariate analysis
Caraballo 2011106Clinical description of EEG in childhood absences
Carman 2013108Multivariate analysis does not include any predictors relevant to the review question. Mostly looked at socio-demographic, birthweight, consanguinity, and parents’ age and education
Carvalho 2001112No multivariate analysis
Casetta 2002114Investigation of pre-, mid- and post-natal risk factors for cryptogenic and idiopathic epilepsy
Chahine 2006118Narrative review. No extractable data
Chahine 2006119Narrative review. No extractable data
Chen 2010125Univariate analysis
Chen 2015126Univariate analysis
Chiaretti 2000128Univariate analysis
Ciceri 2011132Review
Covanis 1992139Univariate analysis. Early prognostic signs of absence epilepsy
Dai 2006141Narrative review. No extractable data
Daoud 2003143Univariate analysis
Datta 2005145Addresses a different question. To determine which factors contribute most to psychopathology in children with epilepsy. No predictors of interest in the multivariate analysis (sociodemographic, treatments, seizure variables including type, duration and frequency)
Dennis 1978153Book chapter
Dhiman 2014156Clinical description and suggestion for new classification
DiMario 2006158Narrative review. No extractable data
Ellenberg 1986170Addresses a different question. The impact of seizures on children’s intellectual performance
Ellenberg 1978171Addresses a different question. Investigates whether intellectual deterioration is caused by seizures in children
Emam 2009173Addresses a different question. Pattern, risk factors, diagnosis and outcome of stroke. Does not present the results of a multivariate analysis
Espeche 2010175No multivariate analysis
Espeche 2011176No multivariate analysis. Analysis of electro-clinical features and evolution of patients with benign infantile seizures associated with paroxysmal dyskinesia
Ettinger 1999178Wrong population (adults)
Fattal-Valevski 2013180Addresses a different question. Clinical description of paediatric brain tumours that present with seizures
Fois 1982185No multivariate analysis
Fois 1988186No multivariate analysis
Geelhoed 2005194Addresses a different question. Accuracy of models in predicting long-term outcome of epilepsy
Graves 2012207Narrative summary. Recommendations for practice
Hamati-Haddad 1998212Addresses a different question. Incidence of febrile convulsions in an epilepsy clinical population and relates presence and characteristics of febrile convulsions to the localisation of subsequent epilepsy
Hansen 2015214Survey. No multivariate analysis
Hauser 1970220Narrative summary. No extractable data
Heijbel 1980223Univariate analysis only
Horrocks 2005230Addresses a different question. Clinical description of the features of a series of children with anoxic-epileptic seizures
Hrastovec 2012231No multivariate analysis
Huang 1998233No multivariate analysis
Huguenard 2016236No multivariate analysis
Kamiishi 1994255No multivariate analysis. Follow-up of childhood absence epilepsy with a history of febrile convulsions
Kannoth 2009256Wrong population. Includes adults and children (mean age 32 years, range 6–85)
Karasalihoglu 2003258Multivariate analysis does not include variables of interest (for example, history of birth asphyxia, type of seizure, polypharmacy)
Kim 2012269Addresses a different question. Clinical and video-EEG-polymyographic study of paroxysmal non-epileptic motor event
King 1999270Addresses a different question. Looking at whether MRI and EEG would reveal abnormal clinical features of benign partial seizures of adolescents
Kirkpatrick 1998271Narrative literature review
Koo 1993275No multivariate analysis
Korff 2005277Addresses a different question. Eye closure during paroxysmal events and link to seizures
Kristensen 1992280No multivariate analysis
Krumholz 1983282No multivariate analysis
Ku 2014283Long-term (11 years) follow-up of children with febrile seizures. Logistic regression includes sex, urbanisation and occupation as variables. No predictors of interest to our review question
Lal 2014286Univariate analysis only
Lee 2016294Long-term follow-up to identify prognostic factors that can predict epilepsy in children with febrile seizures
Lee 1989297Univariate analysis only
Mallick 2014315Univariate analysis. Epidemiology and clinical features of childhood arterial ischemic stroke
Matsumoto 1985317Addresses a different question. Predictors of long-term outcomes if convulsive disorders
Matsumoto 2013318Unobtainable
Metrick 1991328No multivariate analysis
Miano 2010329Univariate analysis only
Neligan 2012343Prospective cohort study looking at long-term risk of developing epilepsy after febrile seizures (follow-up to 20 years)
Nelson 1978344Addresses a different question. Looking at death, motor disabilities and recurrence of seizure. No multivariate analysis
Nevo 1995348Addresses a different question. Risk factors for seizures not seizures as risk factors. Multivariate analysis includes cerebral palsy, mental retardation, febrile seizures and prematurity as variables
O’Brien 1981355Narrative summary. No multivariate analysis or extractable data
Ogunniyi 1987360No multivariate analysis. Risk factors investigated include febrile seizures, head trauma, previous immunisation, use of psychotropic drugs and stimulants, haemoglobinopathy and syphilis
Ogunrin 2014361Cross sectional case-control study. No multivariate analysis
Park 2015369Univariate analysis
Patel 2007372Univariate analysis. Compares clinical features of non-epileptic seizures between <13 year olds and >13 year olds
Pavlidou 2013373Long-term follow-up of children with febrile seizures. No association of symptoms
Pearce 1979375No multivariate analysis. Looking at risk factors as long-term predictors in children with convulsive disorder
Per 2014376No multivariate analysis
Plioplys 2014382Psychogenic non-epileptic seizures. Only data reported from logistic regression is somatic psychiatric and adversity variables. No predictors relevant to our review question
Plioplys 2016383Addresses a different question. Risk factors for comorbid psychopathology in youth with psychogenic non-epileptic seizures
Proulx 1993388No multivariate analysis. Addresses a different question. Assessment of BP measurement in children admitted to PICU for hypertensive crisis or status epilepticus to determine whether this can differentiate between the 2 conditions. Reports sensitivity, specificity, NPV and PPV
Rossiter 1977409Univariate analysis only. Descriptive statistics of convulsions in the first year of life
Saemundsen 2007413No multivariate analysis
Saltik 2003417No multivariate analysis
Sehgal 1979422Univariate analysis. Recurrence of febrile seizures
Seki 1981423Univariate analysis only
Sfaihi 2012424Epidemiological study. Univariate analysis only
Silver 2008427Addresses a different question
Trinka 2002447No multivariate analysis
Ueoka 1980450Abstract on follow-up of children with febrile convulsions
Vaghani 2013452No multivariate analysis
Verduyn 1992456Descriptive study. No extractable data
Verity 1991457No multivariate analysis
Verrotti 2000458No multivariate analysis
Vincentiis 2006461No multivariate analysis. Risk factors for psychogenic non-epileptic seizures in children already diagnosed with epilepsy
Visser 2010462Investigates the prenatal and perinatal factors that may predict the incidence of paroxysmal epileptic and non-epileptic disorders within the first year of life. No predictors of interest in the multivariate analysis
Visser 2012463No predictors of interest in the multivariate analysis (examples include maternal indicators and birthweight)
Wakamoto 2011466Clinical characteristics of childhood absences
Wallace 1984468Narrative review. No extractable data
Wallace 1979469No multivariate analysis
Wang 2008470Looked at scoring system based on frequency of seizures. Data not relevant to our review question
Wiebe 2008474Systematic review
Yang 1995479No multivariate analysis
Yilmaz 2013480Unobtainable

From: Appendix L, Excluded clinical studies

Cover of Suspected neurological conditions
Suspected neurological conditions: recognition and referral.
NICE Guideline, No. 127.
National Guideline Centre (UK).
Copyright © NICE May 2019.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.