| Criterion | Explanation |
|---|---|
| Population | Women who require treatment for hypertension. Setting: hospital or community |
| Intervention/Exposure | Maternal use of beta-blocker or mixed alpha/beta-blocker during late pregnancy and peripartum period, with consideration of timing and duration of use. |
| Comparator | Women not using these agents in late pregnancy. |
| Outcome |
Important outcomes: Baby: hypoglycaemia, need for additional treatment for hypoglycaemia, birthweight centile. (Consideration should be given to use of routinely collected data for determination of some outcomes) |
| Study design | A variety of study designs may be suitable, but consideration of a cohort design (with comparator data) should be included. |
| Timeframe | Minimum duration of follow-up: To primary discharge of woman and baby. |
From: Evidence review for interventions for chronic hypertension
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