mettl2a methyltransferase 2A, methylcytidine [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mettl2aprovided by ZNC
Official Full Name: methyltransferase 2A, methylcytidineprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-462
See related: Ensembl:ENSDARG00000008105 AllianceGenome:ZFIN:ZDB-GENE-050417-462
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110598
Summary: Predicted to enable tRNA (cytosine-3-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to act upstream of or within methylation and tRNA processing. Orthologous to several human genes including METTL2A (methyltransferase 2A, methylcytidine). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 3

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (19665355..19682816)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (19515615..19533076)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (cytidine) methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables tRNA (cytidine-3-)-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA methylation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: tRNA N(3)-methylcytidine methyltransferase METTL2

Names: methyltransferase like 2; methyltransferase like 2A; methyltransferase-like protein 2-A

NP_001017902.1

EC 2.1.1.-

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.