U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CABIN1 calcineurin binding protein 1 [ Homo sapiens (human) ]

Gene ID: 23523, updated on 3-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
CABIN1provided by HGNC
Official Full Name
calcineurin binding protein 1provided by HGNC
Primary source
HGNC:HGNC:24187
See related
Ensembl:ENSG00000099991 MIM:604251; AllianceGenome:HGNC:24187
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CAIN; PPP3IN; KB-318B8.7
Summary
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
Expression
Ubiquitous expression in thyroid (RPKM 6.8), testis (RPKM 6.2) and 25 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CABIN1 in Genome Data Viewer
Location:
22q11.23
Exon count:
40
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (24011304..24178628)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (24472930..24640242)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (24407754..24574596)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372959 Neighboring gene glutathione S-transferase theta 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24487229-24487730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24487731-24488230 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24527017-24527518 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24540118-24540852 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24540853-24541588 Neighboring gene Sharpr-MPRA regulatory region 1007 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13543 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18761 Neighboring gene skeletal muscle cis-regulatory module in CABIN1 intron Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24571075-24571934 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18762 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18763 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24585541-24586182 Neighboring gene MPRA-validated peak4472 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18764 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18765 Neighboring gene sushi domain containing 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24601258-24602226 Neighboring gene uncharacterized LOC124905090 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24609597-24610123

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Endogenous protein inhibitors of calcineurin. Liu JO. Biochem Biophys Res Commun, 2003 Nov 28. PMID 14623296
  2. Selection of choriocarcinoma-associated genes using bioinformatics. Li XN, et al. Di Yi Jun Yi Da Xue Xue Bao, 2005 Jan. PMID 15683985
  3. A case-control association analysis of CABIN1 with schizophrenia in a Japanese population. Watanabe Y, et al. J Hum Genet, 2010 Mar. PMID 20075944
  4. A Molecular Prospective for HIRA Complex Assembly and H3.3-Specific Histone Chaperone Function. Ricketts MD, et al. J Mol Biol, 2017 Jun 30. PMID 27871933, Free PMC Article
  5. EBV-encoded LMP-1 sensitizes nasopharyngeal carcinoma cells to genotoxic drugs by down-regulating Cabin1 expression. Chang PY, et al. J Cell Physiol, 2014 Mar. PMID 23939952

See all (72) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. analysis of the trimeric HIRA, UBN1 and CABIN1 H3.3 histone chaperone complex
    Title: Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit.
  2. Results indicate an important role for LMP1 and Cabin1 in regulating apoptosis in nasopharyngeal carcinoma cells in response to genotoxic stress.
    Title: EBV-encoded LMP-1 sensitizes nasopharyngeal carcinoma cells to genotoxic drugs by down-regulating Cabin1 expression.
  3. Two new susceptibility loci for amyotrophic lateral sclerosis in the Han Chinese population in chromosome 1, CAMK1G and chromosome 22, SUSD2 and CABIN1.
    Title: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.
  4. Our findings demonstrate that hCABIN-1 plays a critical role in promoting apoptosis of fibroblast-like synoviocytes and in attenuating inflammation and cartilage and bone destruction in rheumatoid arthritis.
    Title: Regulation of inflammatory responses and fibroblast-like synoviocyte apoptosis by calcineurin-binding protein 1 in mice with collagen-induced arthritis.
  5. NHRD domain of UBN1 as being an essential region for HIRA interaction and chromatin organization by the HUCA complex
    Title: Identification of an ubinuclein 1 region required for stability and function of the human HIRA/UBN1/CABIN1/ASF1a histone H3.3 chaperone complex.
  6. Data show that, like HIRA, UBN1, and ASF1a, CABIN1 is involved in heterochromatinization of the genome of senescent human cells.
    Title: Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex.
  7. CABIN1 may not confer increased susceptibility for schizophrenia in the Japanese population.
    Title: A case-control association analysis of CABIN1 with schizophrenia in a Japanese population.
  8. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
    Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  9. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  10. the association of CAIN with intracellular domains involved in mGluR/G protein coupling provides a mechanism by which Group I mGluR endocytosis and signaling are regulated
    Title: Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.
EBI GWAS Catalog
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
EBI GWAS Catalog

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • KIAA0330

Gene Ontology Provided by GOA

Function Evidence Code Pubs
contributes_to nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphatase inhibitor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in nucleosome assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in aggresome IDA
Inferred from Direct Assay
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
calcineurin-binding protein cabin-1
Names
calcineurin binding protein cabin 1
calcineurin inhibitor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_047136.1 RefSeqGene

    Range
    5113..172437
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001199281.1 → NP_001186210.1  calcineurin-binding protein cabin-1 isoform a

    See identical proteins and their annotated locations for NP_001186210.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AB002328, AL703593
    Consensus CDS
    CCDS13823.1
    UniProtKB/Swiss-Prot
    G5E9F3, Q6PHY0, Q9Y460, Q9Y6J0
    Related
    ENSP00000381364.2, ENST00000398319.6
    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2156 → 2190
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1945 → 2030
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:2002 → 2130
    RelB_transactiv; RelB transactivation domain

  2. NM_001201429.2 → NP_001188358.1  calcineurin-binding protein cabin-1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AB002328, AC253536, AF072441, BC054497
    Consensus CDS
    CCDS74830.1
    UniProtKB/TrEMBL
    A0A087WWW8
    Related
    ENSP00000480560.1, ENST00000617531.4
    Conserved Domains (4) summary
    COG0457
    Location:34 → 210
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2106 → 2140
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1864 → 2107
    Atrophin-1; Atrophin-1 family

  3. NM_012295.4 → NP_036427.1  calcineurin-binding protein cabin-1 isoform a

    See identical proteins and their annotated locations for NP_036427.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AC253536, AF072441
    Consensus CDS
    CCDS13823.1
    UniProtKB/Swiss-Prot
    G5E9F3, Q6PHY0, Q9Y460, Q9Y6J0
    Related
    ENSP00000263119.5, ENST00000263119.10
    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2156 → 2190
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1945 → 2030
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:2002 → 2130
    RelB_transactiv; RelB transactivation domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    24011304..24178628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441218.1 → XP_047297174.1  calcineurin-binding protein cabin-1 isoform X4

  2. XM_047441219.1 → XP_047297175.1  calcineurin-binding protein cabin-1 isoform X6

    UniProtKB/Swiss-Prot
    G5E9F3, Q6PHY0, Q9Y460, Q9Y6J0

  3. XM_047441226.1 → XP_047297182.1  calcineurin-binding protein cabin-1 isoform X12

  4. XM_047441232.1 → XP_047297188.1  calcineurin-binding protein cabin-1 isoform X15

  5. XM_024452184.2 → XP_024307952.1  calcineurin-binding protein cabin-1 isoform X1

    Conserved Domains (4) summary
    COG0457
    Location:34 → 210
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2191 → 2225
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1949 → 2192
    Atrophin-1; Atrophin-1 family

  6. XM_047441217.1 → XP_047297173.1  calcineurin-binding protein cabin-1 isoform X4

  7. XM_047441221.1 → XP_047297177.1  calcineurin-binding protein cabin-1 isoform X9

  8. XM_047441224.1 → XP_047297180.1  calcineurin-binding protein cabin-1 isoform X12

  9. XM_047441222.1 → XP_047297178.1  calcineurin-binding protein cabin-1 isoform X10

  10. XM_047441225.1 → XP_047297181.1  calcineurin-binding protein cabin-1 isoform X11

  11. XM_047441236.1 → XP_047297192.1  calcineurin-binding protein cabin-1 isoform X19

  12. XM_047441227.1 → XP_047297183.1  calcineurin-binding protein cabin-1 isoform X13

  13. XM_047441238.1 → XP_047297194.1  calcineurin-binding protein cabin-1 isoform X20

  14. XM_047441240.1 → XP_047297196.1  calcineurin-binding protein cabin-1 isoform X21

  15. XM_047441220.1 → XP_047297176.1  calcineurin-binding protein cabin-1 isoform X8

  16. XM_047441234.1 → XP_047297190.1  calcineurin-binding protein cabin-1 isoform X16

  17. XM_005261419.3 → XP_005261476.1  calcineurin-binding protein cabin-1 isoform X7

    Conserved Domains (4) summary
    COG0457
    Location:14 → 165
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2146 → 2180
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:36 → 64
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1904 → 2147
    Atrophin-1; Atrophin-1 family

  18. XM_047441229.1 → XP_047297185.1  calcineurin-binding protein cabin-1 isoform X14

  19. XM_047441231.1 → XP_047297187.1  calcineurin-binding protein cabin-1 isoform X15

  20. XM_047441244.1 → XP_047297200.1  calcineurin-binding protein cabin-1 isoform X23

  21. XM_047441243.1 → XP_047297199.1  calcineurin-binding protein cabin-1 isoform X22

  22. XM_047441246.1 → XP_047297202.1  calcineurin-binding protein cabin-1 isoform X26

  23. XM_047441249.1 → XP_047297205.1  calcineurin-binding protein cabin-1 isoform X29

  24. XM_005261415.4 → XP_005261472.1  calcineurin-binding protein cabin-1 isoform X1

    Conserved Domains (4) summary
    COG0457
    Location:34 → 210
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2191 → 2225
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1949 → 2192
    Atrophin-1; Atrophin-1 family

  25. XM_006724179.3 → XP_006724242.1  calcineurin-binding protein cabin-1 isoform X3

    Conserved Domains (4) summary
    PHA03247
    Location:1948 → 2200
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:34 → 210
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2162 → 2196
    MEF2_binding; MEF2 binding

  26. XM_005261416.4 → XP_005261473.1  calcineurin-binding protein cabin-1 isoform X2

    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2186 → 2220
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1975 → 2060
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:2032 → 2160
    RelB_transactiv; RelB transactivation domain

  27. XM_017028680.3 → XP_016884169.1  calcineurin-binding protein cabin-1 isoform X5

  28. XM_005261417.4 → XP_005261474.1  calcineurin-binding protein cabin-1 isoform X4

    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2161 → 2195
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1950 → 2035
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:2007 → 2135
    RelB_transactiv; RelB transactivation domain

  29. XM_006724181.3 → XP_006724244.1  calcineurin-binding protein cabin-1 isoform X12

    Conserved Domains (5) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2127 → 2161
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    cl21589
    Location:1909 → 2098
    Relaxase; Relaxase/Mobilization nuclease domain

  30. XM_006724180.3 → XP_006724243.1  calcineurin-binding protein cabin-1 isoform X10

    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2132 → 2166
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1921 → 2006
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:1978 → 2106
    RelB_transactiv; RelB transactivation domain

  31. XM_047441223.1 → XP_047297179.1  calcineurin-binding protein cabin-1 isoform X11

  32. XM_011530026.3 → XP_011528328.1  calcineurin-binding protein cabin-1 isoform X13

    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2126 → 2160
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1915 → 2000
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:1972 → 2100
    RelB_transactiv; RelB transactivation domain

  33. XM_047441237.1 → XP_047297193.1  calcineurin-binding protein cabin-1 isoform X20

  34. XM_047441239.1 → XP_047297195.1  calcineurin-binding protein cabin-1 isoform X21

  35. XM_017028681.3 → XP_016884170.1  calcineurin-binding protein cabin-1 isoform X8

  36. XM_047441235.1 → XP_047297191.1  calcineurin-binding protein cabin-1 isoform X17

  37. XM_047441233.1 → XP_047297189.1  calcineurin-binding protein cabin-1 isoform X16

  38. XM_024452187.2 → XP_024307955.1  calcineurin-binding protein cabin-1 isoform X18

    UniProtKB/TrEMBL
    A0A087WWW8
    Conserved Domains (4) summary
    COG0457
    Location:34 → 210
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2106 → 2140
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1864 → 2107
    Atrophin-1; Atrophin-1 family

  39. XM_047441245.1 → XP_047297201.1  calcineurin-binding protein cabin-1 isoform X25

  40. XM_017028683.3 → XP_016884172.1  calcineurin-binding protein cabin-1 isoform X24

    UniProtKB/Swiss-Prot
    Q9Y6J0
    Related
    ENSP00000384694.2, ENST00000405822.6
    Conserved Domains (6) summary
    sd00006
    Location:90 → 118
    TPR; TPR repeat [structural motif]
    pfam09047
    Location:2077 → 2111
    MEF2_binding; MEF2 binding
    pfam13414
    Location:92 → 155
    TPR_11; TPR repeat
    pfam13424
    Location:36 → 120
    TPR_12; Tetratricopeptide repeat
    pfam15444
    Location:1866 → 1951
    TMEM247; Transmembrane protein 247
    pfam16181
    Location:1923 → 2051
    RelB_transactiv; RelB transactivation domain

  41. XM_024452186.2 → XP_024307954.1  calcineurin-binding protein cabin-1 isoform X7

    Conserved Domains (4) summary
    COG0457
    Location:14 → 165
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd13839
    Location:2146 → 2180
    MEF2_binding; Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1
    sd00006
    Location:36 → 64
    TPR; TPR repeat [structural motif]
    cl26464
    Location:1904 → 2147
    Atrophin-1; Atrophin-1 family

  42. XM_047441228.1 → XP_047297184.1  calcineurin-binding protein cabin-1 isoform X14

  43. XM_047441230.1 → XP_047297186.1  calcineurin-binding protein cabin-1 isoform X15

  44. XM_047441242.1 → XP_047297198.1  calcineurin-binding protein cabin-1 isoform X23

  45. XM_047441241.1 → XP_047297197.1  calcineurin-binding protein cabin-1 isoform X22

  46. XM_047441247.1 → XP_047297203.1  calcineurin-binding protein cabin-1 isoform X27

  47. XM_047441248.1 → XP_047297204.1  calcineurin-binding protein cabin-1 isoform X28

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187633.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    301995..302395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    24472930..24640242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054325320.1 → XP_054181295.1  calcineurin-binding protein cabin-1 isoform X4

  2. XM_054325322.1 → XP_054181297.1  calcineurin-binding protein cabin-1 isoform X6

    UniProtKB/Swiss-Prot
    G5E9F3, Q6PHY0, Q9Y460, Q9Y6J0

  3. XM_054325333.1 → XP_054181308.1  calcineurin-binding protein cabin-1 isoform X12

  4. XM_054325340.1 → XP_054181315.1  calcineurin-binding protein cabin-1 isoform X15

  5. XM_054325314.1 → XP_054181289.1  calcineurin-binding protein cabin-1 isoform X1

  6. XM_054325317.1 → XP_054181292.1  calcineurin-binding protein cabin-1 isoform X3

  7. XM_054325318.1 → XP_054181293.1  calcineurin-binding protein cabin-1 isoform X4

  8. XM_054325327.1 → XP_054181302.1  calcineurin-binding protein cabin-1 isoform X9

  9. XM_054325330.1 → XP_054181305.1  calcineurin-binding protein cabin-1 isoform X12

  10. XM_054325328.1 → XP_054181303.1  calcineurin-binding protein cabin-1 isoform X10

  11. XM_054325331.1 → XP_054181306.1  calcineurin-binding protein cabin-1 isoform X11

  12. XM_054325346.1 → XP_054181321.1  calcineurin-binding protein cabin-1 isoform X19

  13. XM_054325335.1 → XP_054181310.1  calcineurin-binding protein cabin-1 isoform X13

  14. XM_054325347.1 → XP_054181322.1  calcineurin-binding protein cabin-1 isoform X20

  15. XM_054325349.1 → XP_054181324.1  calcineurin-binding protein cabin-1 isoform X21

  16. XM_054325325.1 → XP_054181300.1  calcineurin-binding protein cabin-1 isoform X8

  17. XM_054325343.1 → XP_054181318.1  calcineurin-binding protein cabin-1 isoform X16

  18. XM_054325323.1 → XP_054181298.1  calcineurin-binding protein cabin-1 isoform X7

  19. XM_054325338.1 → XP_054181313.1  calcineurin-binding protein cabin-1 isoform X14

  20. XM_054325339.1 → XP_054181314.1  calcineurin-binding protein cabin-1 isoform X15

  21. XM_054325353.1 → XP_054181328.1  calcineurin-binding protein cabin-1 isoform X23

  22. XM_054325351.1 → XP_054181326.1  calcineurin-binding protein cabin-1 isoform X22

  23. XM_054325356.1 → XP_054181331.1  calcineurin-binding protein cabin-1 isoform X26

  24. XM_054325358.1 → XP_054181333.1  calcineurin-binding protein cabin-1 isoform X30

  25. XM_054325359.1 → XP_054181334.1  calcineurin-binding protein cabin-1 isoform X28

  26. XM_054325360.1 → XP_054181335.1  calcineurin-binding protein cabin-1 isoform X29

  27. XM_054325315.1 → XP_054181290.1  calcineurin-binding protein cabin-1 isoform X1

  28. XM_054325316.1 → XP_054181291.1  calcineurin-binding protein cabin-1 isoform X2

  29. XM_054325321.1 → XP_054181296.1  calcineurin-binding protein cabin-1 isoform X5

  30. XM_054325319.1 → XP_054181294.1  calcineurin-binding protein cabin-1 isoform X4

  31. XM_054325332.1 → XP_054181307.1  calcineurin-binding protein cabin-1 isoform X12

  32. XM_054325329.1 → XP_054181304.1  calcineurin-binding protein cabin-1 isoform X10

  33. XM_054325334.1 → XP_054181309.1  calcineurin-binding protein cabin-1 isoform X11

  34. XM_054325336.1 → XP_054181311.1  calcineurin-binding protein cabin-1 isoform X13

  35. XM_054325348.1 → XP_054181323.1  calcineurin-binding protein cabin-1 isoform X21

  36. XM_054325326.1 → XP_054181301.1  calcineurin-binding protein cabin-1 isoform X8

  37. XM_054325344.1 → XP_054181319.1  calcineurin-binding protein cabin-1 isoform X17

  38. XM_054325342.1 → XP_054181317.1  calcineurin-binding protein cabin-1 isoform X16

  39. XM_054325345.1 → XP_054181320.1  calcineurin-binding protein cabin-1 isoform X18

    UniProtKB/TrEMBL
    A0A087WWW8

  40. XM_054325355.1 → XP_054181330.1  calcineurin-binding protein cabin-1 isoform X25

  41. XM_054325354.1 → XP_054181329.1  calcineurin-binding protein cabin-1 isoform X24

  42. XM_054325324.1 → XP_054181299.1  calcineurin-binding protein cabin-1 isoform X7

  43. XM_054325337.1 → XP_054181312.1  calcineurin-binding protein cabin-1 isoform X14

  44. XM_054325341.1 → XP_054181316.1  calcineurin-binding protein cabin-1 isoform X15

  45. XM_054325352.1 → XP_054181327.1  calcineurin-binding protein cabin-1 isoform X23

  46. XM_054325350.1 → XP_054181325.1  calcineurin-binding protein cabin-1 isoform X22

  47. XM_054325357.1 → XP_054181332.1  calcineurin-binding protein cabin-1 isoform X27

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y6J0.1 GenPept UniProtKB/Swiss-Prot:Q9Y6J0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous