Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Pr55(Gag)
|
gag
|
Deletion of residues 32-51 in the N-terminus of HIV-1 MA impairs both HIV-1 Gag interaction with KIF4 and its ability to induce microtubule (MT) acetylation, suggesting that MA-mediated targeting of KIF4 by Gag regulates MT stability in early infection |
PubMed
|
|
gag
|
Disrupting the function of KIF4 leads Gag transient accumulation in discrete, perinuclear, nonendocytic clusters that co-localize with endogenous KIF4, Ubc9, and SUMO |
PubMed
|
|
gag
|
Binding of HIV-1 Gag to KIF-4 may play a role in HIV-1 Gag polyprotein transport from the cytoplasm to the cell membrane |
PubMed
|
|
gag
|
Binding of human KIF-4 to HIV-1 Gag is presumed based on homology to murine KIF-4 which binds to an HIV-1 Gag intermediate, consisting of Matrix and Capsid, in a yeast two-hybrid assay and in co-immunoprecipitation assays |
PubMed
|
matrix
|
gag
|
Deletion of residues 32-51 in the N-terminus of HIV-1 MA impairs both HIV-1 Gag interaction with KIF4 and its ability to induce microtubule (MT) acetylation, suggesting that MA-mediated targeting of KIF4 by Gag regulates MT stability in early infection |
PubMed
|
|
gag
|
Binding of HIV-1 Matrix to KIF-4 may play a role in HIV-1 Gag polyprotein relocalize from the cytoplasm to the cell membrane |
PubMed
|
|
gag
|
Binding of human KIF-4 to HIV-1 Matrix is presumed based on homology to murine KIF-4 which binds to an HIV-1 Gag intermediate, consisting of Matrix and Capsid, in a yeast two-hybrid assay and in co-immunoprecipitation assays |
PubMed
|
Go to the HIV-1, Human Interaction Database