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slmapb sarcolemma associated protein b [ Danio rerio (zebrafish) ]

Gene ID: 393146, updated on 17-Aug-2024

Summary

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Official Symbol
slmapbprovided by ZNC
Official Full Name
sarcolemma associated protein bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-809
See related
Ensembl:ENSDARG00000020764 AllianceGenome:ZFIN:ZDB-GENE-040426-809
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
slmap; zgc:55817
Summary
Predicted to be involved in protein localization to plasma membrane; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in epidermis; median fin fold; nervous system; neural crest; and pharyngeal arch 3-7 skeleton. Orthologous to human SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See slmapb in Genome Data Viewer
Location:
chromosome: 23
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (19589821..19604413)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (19663722..19678070)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene dynein, axonemal, heavy chain 12 Neighboring gene ATPase H+ transporting accessory protein 1 like b Neighboring gene filamin B, beta (actin binding protein 278) Neighboring gene abhydrolase domain containing 6, acylglycerol lipase b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Differential protein profile in zebrafish (Danio rerio) brain under the joint exposure of methyl parathion and cadmium. Ling XP, et al. Environ Sci Pollut Res Int, 2012 Nov. PMID 22767353
  2. Analysis and functional evaluation of the hair-cell transcriptome. McDermott BM Jr, et al. Proc Natl Acad Sci U S A, 2007 Jul 10. PMID 17606911, Free PMC Article
  3. Proteomics of early zebrafish embryos. Link V, et al. BMC Dev Biol, 2006 Jan 13. PMID 16412219, Free PMC Article
  4. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Shkumatava A, et al. Genes Dev, 2009 Feb 15. PMID 19240133, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC55817

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sarcolemma associated protein b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200177.1 → NP_956471.1  sarcolemma associated protein b

    See identical proteins and their annotated locations for NP_956471.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045462
    UniProtKB/TrEMBL
    Q7ZVP6
    Related
    ENSDARP00000024693.6, ENSDART00000021231.8
    Conserved Domains (1) summary
    TIGR02168
    Location:66 → 350
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    19589821..19604413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162050.4 → XP_005162107.1  sarcolemma associated protein b isoform X1

    UniProtKB/TrEMBL
    A0A8M2B8Z6
    Conserved Domains (1) summary
    TIGR02168
    Location:66 → 352
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395361.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    117731..131903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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