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bzw2 basic leucine zipper and W2 domains 2 [ Danio rerio (zebrafish) ]

Gene ID: 393892, updated on 2-Nov-2024

Summary

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Official Symbol
bzw2provided by ZNC
Official Full Name
basic leucine zipper and W2 domains 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-746
See related
Ensembl:ENSDARG00000035918 AllianceGenome:ZFIN:ZDB-GENE-040426-746
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:eu935; zgc:55580
Summary
Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm. Is expressed in myotome. Orthologous to human BZW2 (basic leucine zipper and W2 domains 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See bzw2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (31009696..31042597, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (31422383..31455317, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene syncoilin, intermediate filament protein Neighboring gene retinoblastoma binding protein 4 Neighboring gene ankyrin repeat and MYND domain-containing protein 2-like Neighboring gene sclerostin domain containing 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic and evolutionary relationships and developmental expression patterns of the zebrafish twist gene family. Yeo GH, et al. Dev Genes Evol, 2009 Jun. PMID 19565261
  2. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Zhang Y, et al. Cell Rep, 2017 Jan 10. PMID 28076796, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC55580

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
eIF5-mimic protein 1
Names
DKEYP-25A3.4
basic leucine zipper and W2 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200918.1 → NP_957212.1  eIF5-mimic protein 1

    See identical proteins and their annotated locations for NP_957212.1

    Status: PROVISIONAL

    Source sequence(s)
    BC048052
    UniProtKB/Swiss-Prot
    Q1LUC1
    Related
    ENSDARP00000123337.1, ENSDART00000136213.3
    Conserved Domains (1) summary
    cd11560
    Location:220 → 410
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    31009696..31042597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159605.4 → XP_005159662.1  eIF5-mimic protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005159662.1

    UniProtKB/Swiss-Prot
    Q1LUC1, Q7ZUN5
    UniProtKB/TrEMBL
    A0A8M9PN66
    Related
    ENSDARP00000152624.1, ENSDART00000190949.1
    Conserved Domains (1) summary
    cd11560
    Location:220 → 410
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

  2. XM_068215051.1 → XP_068071152.1  eIF5-mimic protein 1 isoform X1

  3. XM_068215050.1 → XP_068071151.1  eIF5-mimic protein 1 isoform X1

  4. XM_068215049.1 → XP_068071150.1  eIF5-mimic protein 1 isoform X1

  5. XM_005159606.2 → XP_005159663.1  eIF5-mimic protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005159663.1

    UniProtKB/Swiss-Prot
    Q1LUC1, Q7ZUN5
    UniProtKB/TrEMBL
    A0A8M9PN66
    Conserved Domains (1) summary
    cd11560
    Location:220 → 410
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1LUC1.1 GenPept UniProtKB/Swiss-Prot:Q1LUC1

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