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gstk1 glutathione S-transferase kappa 1 [ Danio rerio (zebrafish) ]

Gene ID: 436833, updated on 17-Sep-2024

Summary

Official Symbol
gstk1provided by ZNC
Official Full Name
glutathione S-transferase kappa 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-298
See related
Ensembl:ENSDARG00000056510 Ensembl:ENSDARG00000093119 AllianceGenome:ZFIN:ZDB-GENE-040718-298
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92763
Summary
Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in mitochondrion and peroxisome. Orthologous to human GSTK1 (glutathione S-transferase kappa 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See gstk1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (31981296..32013934, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (32055175..32059919, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene polyhomeotic homolog 1 Neighboring gene serine/threonine/tyrosine kinase 1b Neighboring gene glutathione S-transferase kappa 4 Neighboring gene membrane bound O-acyltransferase domain containing 7 Neighboring gene transmembrane channel-like 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glutathione peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glutathione peroxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
glutathione S-transferase kappa 1
NP_001002560.1
XP_005158401.1
XP_021322619.2
XP_068070042.1
XP_068070043.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002560.1NP_001002560.1  glutathione S-transferase kappa 1

    See identical proteins and their annotated locations for NP_001002560.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076240
    UniProtKB/TrEMBL
    A0A8M1N0N7, Q6DGU9
    Related
    ENSDARP00000035103.7, ENSDART00000030282.9
    Conserved Domains (1) summary
    cd03021
    Location:6214
    DsbA_GSTK; DsbA family, Glutathione (GSH) S-transferase Kappa (GSTK) subfamily; GSTK is a member of the GST family of enzymes which catalyzes the transfer of the thiol of GSH to electrophilic substrates. It is specifically located in the mitochondria and ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    31981296..32013934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466944.2XP_021322619.2  glutathione S-transferase kappa 1 isoform X3

    Related
    ENSDARP00000116858.1, ENSDART00000148176.3
  2. XM_068213942.1XP_068070043.1  glutathione S-transferase kappa 1 isoform X1

  3. XM_068213941.1XP_068070042.1  glutathione S-transferase kappa 1 isoform X1

  4. XM_005158344.5XP_005158401.1  glutathione S-transferase kappa 1 isoform X2

    See identical proteins and their annotated locations for XP_005158401.1

    UniProtKB/TrEMBL
    A0A8M1N0N7, Q6DGU9
    Conserved Domains (1) summary
    cd03021
    Location:6214
    DsbA_GSTK; DsbA family, Glutathione (GSH) S-transferase Kappa (GSTK) subfamily; GSTK is a member of the GST family of enzymes which catalyzes the transfer of the thiol of GSH to electrophilic substrates. It is specifically located in the mitochondria and ...