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phf21aa PHD finger protein 21Aa [ Danio rerio (zebrafish) ]

Gene ID: 497383, updated on 28-Oct-2024

Summary

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Official Symbol
phf21aaprovided by ZNC
Official Full Name
PHD finger protein 21Aaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050208-99
See related
Ensembl:ENSDARG00000006878 AllianceGenome:ZFIN:ZDB-GENE-050208-99
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7138823; si:dkey-23n7.9
Summary
Predicted to enable chromatin binding activity. Predicted to be part of histone deacetylase complex. Is expressed in central nervous system and neural plate. Orthologous to human PHF21A (PHD finger protein 21A). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See phf21aa in Genome Data Viewer
Location:
chromosome: 7
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (38821438..38861745, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (38550183..38590485, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene zgc:110699 Neighboring gene ATG13 autophagy related 13 homolog (S. cerevisiae) Neighboring gene harbinger transposase derived 1 Neighboring gene cAMP responsive element binding protein 3-like 1 Neighboring gene uncharacterized LOC101882371 Neighboring gene diacylglycerol kinase, zeta a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. ZebraShare: a new venue for rapid dissemination of zebrafish mutant data. DeLaurier A, et al. PeerJ, 2021. PMID 33954026, Free PMC Article
  2. Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts. Zhang J, et al. Front Endocrinol (Lausanne), 2018. PMID 30631305, Free PMC Article
  3. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PHD finger protein 21Aa
Names
PHD finger protein 21A
mutant PHD finger protein 21Aa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328015.1 → NP_001314944.1  PHD finger protein 21Aa

    Status: VALIDATED

    Source sequence(s)
    BX957256
    UniProtKB/TrEMBL
    A0A8M1P9R5, F1RCE3
    Related
    ENSDARP00000028385.8, ENSDART00000037361.10
    Conserved Domains (1) summary
    PHA03247
    Location:75 → 374
    PHA03247; large tegument protein UL36; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    38821438..38861745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009303358.4 → XP_009301633.1  PHD finger protein 21Aa isoform X2

    UniProtKB/TrEMBL
    A0A1D5NSA1, A0A8M3BB60
    Related
    ENSDARP00000142711.1, ENSDART00000173953.2
    Conserved Domains (1) summary
    PHA03247
    Location:87 → 402
    PHA03247; large tegument protein UL36; Provisional

  2. XM_009303359.4 → XP_009301634.1  PHD finger protein 21Aa isoform X3

    UniProtKB/TrEMBL
    A0A8M3AUE6
    Conserved Domains (1) summary
    pfam01017
    Location:21 → 98
    STAT_alpha; STAT protein, all-alpha domain

  3. XM_009303357.4 → XP_009301632.1  PHD finger protein 21Aa isoform X1

    UniProtKB/TrEMBL
    A0A1D5NSS3, A0A8M3AUG0
    Related
    ENSDARP00000142891.1, ENSDART00000173629.2
    Conserved Domains (1) summary
    pfam01017
    Location:21 → 98
    STAT_alpha; STAT protein, all-alpha domain

RNA

  1. XR_662173.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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