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ft2 alpha(1,3)fucosyltransferase gene 2 [ Danio rerio (zebrafish) ]

Gene ID: 792063, updated on 28-Oct-2024

Summary

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Official Symbol
ft2provided by ZNC
Official Full Name
alpha(1,3)fucosyltransferase gene 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-990715-18
See related
Ensembl:ENSDARG00000109567 AllianceGenome:ZFIN:ZDB-GENE-990715-18
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zFT2; zgc:194457
Summary
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in Golgi cisterna membrane and Golgi membrane. [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See ft2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (5637626..5641825)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (5719377..5724590)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene junction plakoglobin b Neighboring gene WAS/WASL interacting protein family, member 2b Neighboring gene si:ch211-264f5.2 Neighboring gene alpha(1,3)fucosyltransferase gene 1 Neighboring gene pyruvate dehydrogenase kinase 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of two zebrafish alpha(1,3)fucosyltransferase genes developmentally regulated in embryogenesis. Kageyama N, et al. J Biochem, 1999 Apr. PMID 10101300
  2. Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis. Han Y, et al. Toxicol Appl Pharmacol, 2017 Jul 15. PMID 28465218
  3. Neuroepithelial cells require fucosylated glycans to guide the migration of vagus motor neuron progenitors in the developing zebrafish hindbrain. Ohata S, et al. Development, 2009 May. PMID 19369395
  4. Mapping the expressed glycome and glycosyltransferases of zebrafish liver cells as a relevant model system for glycosylation studies. Vanbeselaere J, et al. J Proteome Res, 2012 Apr 6. PMID 22352757
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha(1,3)fucosyltransferase gene 2
NP_001122245.1
XP_005168265.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128773.1 → NP_001122245.1  alpha(1,3)fucosyltransferase gene 2

    See identical proteins and their annotated locations for NP_001122245.1

    Status: PROVISIONAL

    Source sequence(s)
    BC163660
    UniProtKB/TrEMBL
    A0A8M1NHY8, B3DJZ1
    Related
    ENSDARP00000146547.1, ENSDART00000179987.1
    Conserved Domains (2) summary
    pfam00852
    Location:216 → 385
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:98 → 199
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    5637626..5641825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005168208.5 → XP_005168265.1  alpha(1,3)fucosyltransferase gene 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BFK1
    Conserved Domains (2) summary
    pfam00852
    Location:231 → 400
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:113 → 214
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
Nucleotide Protein Strain
Heading Accession and Version

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