U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    ISN1 IMP 5'-nucleotidase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854326, updated on 4-Jan-2025

    Summary

    Official Symbol
    ISN1
    Official Full Name
    IMP 5'-nucleotidase
    Primary source
    SGD:S000005681
    Locus tag
    YOR155C
    See related
    AllianceGenome:SGD:S000005681; FungiDB:YOR155C; VEuPathDB:YOR155C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables IMP 5'-nucleotidase activity. Involved in inosine salvage; nicotinamide riboside biosynthetic process; and nicotinic acid riboside biosynthetic process. [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ISN1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (626628..627980, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette multidrug transporter PDR5 Neighboring gene Slp1p Neighboring gene SUMO ligase NFI1 Neighboring gene proteasome core particle subunit beta 2

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables IMP 5'-nucleotidase activity  
    enables IMP 5'-nucleotidase activity PubMed 
    enables IMP 5'-nucleotidase activity  
    enables hydrolase activity  
    enables magnesium ion binding  
    enables metal ion binding  
    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    IMP 5'-nucleotidase
    NP_014798.3
    • Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase; catalyzes the breakdown of IMP to inosine; responsible for production of nicotinamide riboside and nicotinic acid riboside; tetrameric form negatively regulated by inosine and ATP; expression positively regulated by nicotinic acid and glucose availability; does not show similarity to known 5'-nucleotidases from other organisms

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      626628..627980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183574.3NP_014798.3  TPA: IMP 5'-nucleotidase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014798.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2L2, Q99312
      UniProtKB/TrEMBL
      A6ZNZ9, B3LJI7, B5VS43, C7GN69, C8ZGR3, G2WN27, N1P389
      Conserved Domains (1) summary
      pfam06437
      Location:1443
      ISN1; IMP-specific 5'-nucleotidase
    External link. Please review our privacy policy.